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Info page for variable 8176026 (#16756)

Internal ID: 16756
Label in dataset: 8176026
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Accession Number: NM_001456
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Gene Information: Entrez ID 2316
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Gene Symbol FLNA, filamin A, alpha
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miRBase: Accession -na-
Chromosome location:
Chromosome Location
X -153,576,899 (antisense)
KEGG Pathways:
Pathway Description
04010 MAPK signaling pathway
04510 Focal adhesion
Gene Ontology:
GOID Evidence Ontology Description(GO Term)
GO:0007195 IMPInferred from Mutant Phenotype BPBiological Process inhibition of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0050821 IMPInferred from Mutant Phenotype BPBiological Process protein stabilization
GO:0031532 IDAInferred from Direct Assay BPBiological Process actin cytoskeleton reorganization
GO:0034394 IDAInferred from Direct Assay BPBiological Process protein localization at cell surface
GO:0042177 IMPInferred from Mutant Phenotype BPBiological Process negative regulation of protein catabolic process
GO:0042993 IMPInferred from Mutant Phenotype BPBiological Process positive regulation of transcription factor import into nucleus
GO:0043113 IDAInferred from Direct Assay BPBiological Process receptor clustering
GO:0043123 IMPInferred from Mutant Phenotype BPBiological Process positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043433 IDAInferred from Direct Assay BPBiological Process negative regulation of transcription factor activity
GO:0045022 IEAInferred from Electronic Annotation BPBiological Process early endosome to late endosome transport
GO:0045184 IDAInferred from Direct Assay BPBiological Process establishment of protein localization
GO:0051220 IMPInferred from Mutant Phenotype BPBiological Process cytoplasmic sequestering of protein
GO:0051764 IDAInferred from Direct Assay BPBiological Process actin crosslink formation
GO:0005886 IDAInferred from Direct Assay CCCellular Component plasma membrane
GO:0005576 EXPInferred from Experiment CCCellular Component extracellular region
GO:0005829 EXPInferred from Experiment CCCellular Component cytosol
GO:0005634 IDAInferred from Direct Assay CCCellular Component nucleus
GO:0005737 IDAInferred from Direct Assay CCCellular Component cytoplasm
GO:0005802 IEAInferred from Electronic Annotation CCCellular Component trans-Golgi network
GO:0005938 IEAInferred from Electronic Annotation CCCellular Component cell cortex
GO:0015629 IDAInferred from Direct Assay CCCellular Component actin cytoskeleton
GO:0005515 IPIInferred from Physical Interaction MFMolecular Function protein binding
GO:0001948 IDAInferred from Direct Assay MFMolecular Function glycoprotein binding
GO:0051015 IDAInferred from Direct Assay MFMolecular Function actin filament binding
GO:0004871 IMPInferred from Mutant Phenotype MFMolecular Function signal transducer activity
GO:0005080 IEAInferred from Electronic Annotation MFMolecular Function protein kinase C binding
GO:0008134 IPIInferred from Physical Interaction MFMolecular Function transcription factor binding
GO:0017048 IDAInferred from Direct Assay MFMolecular Function Rho GTPase binding
GO:0031267 IDAInferred from Direct Assay MFMolecular Function small GTPase binding
GO:0034988 IDAInferred from Direct Assay MFMolecular Function Fc-gamma receptor I complex binding
GO:0034989 IDAInferred from Direct Assay MFMolecular Function GTP-Ral binding
GO:0042803 IDAInferred from Direct Assay MFMolecular Function protein homodimerization activity
GO:0048365 IDAInferred from Direct Assay MFMolecular Function Rac GTPase binding
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Correlation Browser: Daniel Sachse, Sjur Reppe, Kåre Gautvik - 2013.

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