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Info page for variable 8053668 (#5348)

Internal ID: 5348
Label in dataset: 8053668
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Accession Number: NM_004836
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Gene Information: Entrez ID 9451
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Gene Symbol EIF2AK3, eukaryotic translation initiation factor 2-alpha kinase 3
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miRBase: Accession -na-
Chromosome location:
Chromosome Location
2 -88,856,260 (antisense)
KEGG Pathways:
Pathway Description
04141 Protein processing in endoplasmic reticulum
05010 Alzheimer's disease
Gene Ontology:
GOID Evidence Ontology Description(GO Term)
GO:0001501 ISSInferred from Sequence or Structural Similarity BPBiological Process skeletal system development
GO:0001503 IMPInferred from Mutant Phenotype BPBiological Process ossification
GO:0002063 ISSInferred from Sequence or Structural Similarity BPBiological Process chondrocyte development
GO:0006986 IEAInferred from Electronic Annotation BPBiological Process response to unfolded protein
GO:0006468 ISSInferred from Sequence or Structural Similarity BPBiological Process protein amino acid phosphorylation
GO:0006919 ISSInferred from Sequence or Structural Similarity BPBiological Process activation of caspase activity
GO:0006926 IEAInferred from Electronic Annotation BPBiological Process virus-infected cell apoptosis
GO:0006983 IDAInferred from Direct Assay BPBiological Process ER overload response
GO:0007029 ISSInferred from Sequence or Structural Similarity BPBiological Process endoplasmic reticulum organization
GO:0019722 ISSInferred from Sequence or Structural Similarity BPBiological Process calcium-mediated signaling
GO:0007595 IEAInferred from Electronic Annotation BPBiological Process lactation
GO:0009967 IEAInferred from Electronic Annotation BPBiological Process positive regulation of signal transduction
GO:0017148 TASTraceable Author Statement BPBiological Process negative regulation of translation
GO:0019217 IEAInferred from Electronic Annotation BPBiological Process regulation of fatty acid metabolic process
GO:0030073 ISSInferred from Sequence or Structural Similarity BPBiological Process insulin secretion
GO:0030282 ISSInferred from Sequence or Structural Similarity BPBiological Process bone mineralization
GO:0030968 IDAInferred from Direct Assay BPBiological Process endoplasmic reticulum unfolded protein response
GO:0030968 TASTraceable Author Statement BPBiological Process endoplasmic reticulum unfolded protein response
GO:0031018 IMPInferred from Mutant Phenotype BPBiological Process endocrine pancreas development
GO:0031642 ISSInferred from Sequence or Structural Similarity BPBiological Process negative regulation of myelination
GO:0032057 TASTraceable Author Statement BPBiological Process negative regulation of translational initiation in response to stress
GO:0032092 IEAInferred from Electronic Annotation BPBiological Process positive regulation of protein binding
GO:0032933 IEAInferred from Electronic Annotation BPBiological Process SREBP-mediated signaling pathway
GO:0034976 IMPInferred from Mutant Phenotype BPBiological Process response to endoplasmic reticulum stress
GO:0051260 IMPInferred from Mutant Phenotype BPBiological Process protein homooligomerization
GO:0045444 IEAInferred from Electronic Annotation BPBiological Process fat cell differentiation
GO:0046777 IDAInferred from Direct Assay BPBiological Process protein amino acid autophosphorylation
GO:0046777 IMPInferred from Mutant Phenotype BPBiological Process protein amino acid autophosphorylation
GO:0048009 ISSInferred from Sequence or Structural Similarity BPBiological Process insulin-like growth factor receptor signaling pathway
GO:0016020 IEAInferred from Electronic Annotation CCCellular Component membrane
GO:0016021 IEAInferred from Electronic Annotation CCCellular Component integral to membrane
GO:0005783 ISSInferred from Sequence or Structural Similarity CCCellular Component endoplasmic reticulum
GO:0005783 TASTraceable Author Statement CCCellular Component endoplasmic reticulum
GO:0005623 IEAInferred from Electronic Annotation CCCellular Component cell
GO:0005737 ISSInferred from Sequence or Structural Similarity CCCellular Component cytoplasm
GO:0005789 ISSInferred from Sequence or Structural Similarity CCCellular Component endoplasmic reticulum membrane
GO:0005789 NASNon-traceable Author Statement CCCellular Component endoplasmic reticulum membrane
GO:0000166 IEAInferred from Electronic Annotation MFMolecular Function nucleotide binding
GO:0005515 IPIInferred from Physical Interaction MFMolecular Function protein binding
GO:0004672 TASTraceable Author Statement MFMolecular Function protein kinase activity
GO:0004674 ISSInferred from Sequence or Structural Similarity MFMolecular Function protein serine/threonine kinase activity
GO:0004694 IDAInferred from Direct Assay MFMolecular Function eukaryotic translation initiation factor 2alpha kinase activity
GO:0004694 IMPInferred from Mutant Phenotype MFMolecular Function eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 IEAInferred from Electronic Annotation MFMolecular Function ATP binding
GO:0042802 IPIInferred from Physical Interaction MFMolecular Function identical protein binding
GO:0016740 IEAInferred from Electronic Annotation MFMolecular Function transferase activity
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Correlation Browser: Daniel Sachse, Sjur Reppe, Kåre Gautvik - 2013.

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