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Correlations in the blood dataset

A typical search starts with inserting an identifier in the first window of “Search Options”, either Entrez Gene ID (e.g., “1234”), an Accession Number (e.g., “BE644809” or “NM_005715”), a Gene Symbol (e.g., “NR3C1” or “CREB1”, not case-sensitive) or an Affymetrix probe set ID (e.g., “8114814”).

Then, a specific transcript can be traced by inserting a second identifier in window two under “Search Options”. Alternatively, the window may be left open to obtain a list of the transcripts most significantly correlating to the identifier in the first window.

Filling in boxes in the “output options” fields enables restriction of output to e.g., transcripts having specific keywords in Gene Ontology (GO), TFs (genes having “transcription” as part of the Gene Title) or only positive or negative correlations.

(View the full list of available key terms [here]).

Search Options: Find correlations between...
Gene/Label/Number: and (Empty also means "all others")
Output Options
Restrict output to miRs, Transcription factors? (Empty: No restrictions.)
  with keyword:
 KEGG Pathway:
Limit output to rows.
Remove "self correlations", i.e. correlations of a variable with itself
Sort results by positive, negative or absolute value of correlation
Starting timer.
Connected to database on
Searching for user input in variable labels, Entrez IDs, Accession Numbers...
Evaluating targets, filters and restrictions...

Finding correlations with 2 variables:
id Label1 AccNum GeneSym Info Gene Name
15088 8178727 NM_004381 ATF6B link to infopage activating transcription factor 6 beta
15100 8125295 NM_004381 ATF6B link to infopage activating transcription factor 6 beta

Fetching correlation data, please wait...
Getting list of correlations for id 15088.
Getting list of p-values for id 15088.
1 of 2 done.
Getting list of correlations for id 15100.
Getting list of p-values for id 15100.
2 of 2 done.
Calculating corrections for multiple testing (n=34654), please wait...
Done; whole program took 0.139 seconds. Transmitting 50 results:

Column legend:

Rank Label1 Label2 AccNum GeneSym Info Pearson r Raw p Bonferroni FDR (BH)
1 8125295 8178727 NM_004381 ATF6B link to infopage 0.984013 5.227389e-79 1.811499e-74 1.811499e-74
2 8178727 8125295 NM_004381 ATF6B link to infopage 0.984013 5.227389e-79 1.811499e-74 9.057496e-75
3 8125295 8167069 NM_003334 UBA1 link to infopage 0.707952 3.046739e-17 1.055817e-12 3.519389e-13
4 8125295 7996685 NM_014329 EDC4 link to infopage 0.703332 5.985004e-17 2.074043e-12 5.185108e-13
5 8125295 7953569 NM_080549 PTPN6 link to infopage 0.702390 6.856570e-17 2.376076e-12 4.752152e-13
6 8178727 8167069 NM_003334 UBA1 link to infopage 0.696566 1.571915e-16 5.447314e-12 9.078856e-13
7 8178727 7996685 NM_014329 EDC4 link to infopage 0.692233 2.877035e-16 9.970077e-12 1.424297e-12
8 8125295 8029147 NM_199002 ARHGEF1 link to infopage 0.691618 3.132275e-16 1.085459e-11 1.356823e-12
9 8178727 8029147 NM_199002 ARHGEF1 link to infopage 0.687205 5.726595e-16 1.984494e-11 2.204994e-12
10 8178727 7953569 NM_080549 PTPN6 link to infopage 0.679159 1.674789e-15 5.803814e-11 5.803814e-12
11 8125295 8025895 NM_002743 PRKCSH link to infopage 0.678598 1.802476e-15 6.246300e-11 5.678454e-12
12 8125295 7949465 NM_021975 RELA link to infopage 0.676480 2.376075e-15 8.234051e-11 6.861709e-12
13 8178727 8053107 NM_004082 DCTN1 link to infopage 0.675464 2.710623e-15 9.393392e-11 7.225686e-12
14 8125295 7947681 NM_004308 ARHGAP1 link to infopage 0.674692 2.994639e-15 1.037762e-10 7.412587e-12
15 8125295 8053107 NM_004082 DCTN1 link to infopage 0.674640 3.014844e-15 1.044764e-10 6.965093e-12
16 8125295 7930031 NM_004193 GBF1 link to infopage 0.673325 3.570544e-15 1.237336e-10 7.733352e-12
17 8178727 8025895 NM_002743 PRKCSH link to infopage 0.673013 3.716233e-15 1.287823e-10 7.575431e-12
18 8178727 7949465 NM_021975 RELA link to infopage 0.672174 4.137305e-15 1.433742e-10 7.965231e-12
19 8125295 7994889 NM_006662 SRCAP link to infopage 0.666328 8.656974e-15 2.999988e-10 1.578941e-11
20 8125295 8031176 NM_052925 LENG8 link to infopage 0.657929 2.430165e-14 8.421494e-10 4.210747e-11
21 8125295 8004431 NM_000937 POLR2A link to infopage 0.657396 2.591859e-14 8.981829e-10 4.277062e-11
22 8178727 7994889 NM_006662 SRCAP link to infopage 0.655948 3.085537e-14 1.069262e-9 4.860282e-11
23 8125295 7905631 NM_023015 INTS3 link to infopage 0.652801 4.491670e-14 1.556543e-9 6.767579e-11
24 8125295 8041826 NM_020458 TTC7A link to infopage 0.651744 5.090735e-14 1.764143e-9 7.350598e-11
25 8178727 7947681 NM_004308 ARHGAP1 link to infopage 0.650015 6.240377e-14 2.162540e-9 8.650160e-11
26 8125295 8060705 NM_020746 MAVS link to infopage 0.648688 7.290190e-14 2.526342e-9 9.716702e-11
27 8125295 8075343 NM_005877 SF3A1 link to infopage 0.648295 7.632371e-14 2.644922e-9 9.796007e-11
28 8125295 8026315 NM_213560 PKN1 link to infopage 0.647769 8.114666e-14 2.812056e-9 1.004306e-10
29 8178727 8075343 NM_005877 SF3A1 link to infopage 0.647354 8.516052e-14 2.951153e-9 1.017639e-10
30 8125295 8013191 NM_002018 FLII link to infopage 0.646002 9.961962e-14 3.452218e-9 1.150739e-10
31 8178727 8031176 NM_052925 LENG8 link to infopage 0.645638 1.039019e-13 3.600616e-9 1.161489e-10
32 8178727 7930031 NM_004193 GBF1 link to infopage 0.645032 1.114238e-13 3.861281e-9 1.206650e-10
33 8125295 8018324 NM_138619 GGA3 link to infopage 0.642690 1.457794e-13 5.051840e-9 1.530861e-10
34 8125295 7920877 NM_004723 ARHGEF2 link to infopage 0.641535 1.663157e-13 5.763503e-9 1.695148e-10
35 8178727 8026315 NM_213560 PKN1 link to infopage 0.640614 1.846411e-13 6.398551e-9 1.828158e-10
36 8125295 8013486 NM_015276 USP22 link to infopage 0.635528 3.269767e-13 1.133105e-8 3.147514e-10
37 8178727 8041826 NM_020458 TTC7A link to infopage 0.634929 3.494872e-13 1.211113e-8 3.273279e-10
38 8125295 8076137 NM_015374 SUN2 link to infopage 0.633642 4.030684e-13 1.396793e-8 3.675772e-10
39 8125295 7956301 NM_002332 LRP1 link to infopage 0.631705 4.989409e-13 1.729030e-8 4.433410e-10
40 8178727 8004431 NM_000937 POLR2A link to infopage 0.630931 5.431581e-13 1.882260e-8 4.705650e-10
41 8178727 8060705 NM_020746 MAVS link to infopage 0.629530 6.329377e-13 2.193382e-8 5.349713e-10
42 8125295 8084439 NM_182917 EIF4G1 link to infopage 0.629488 6.358471e-13 2.203465e-8 5.246344e-10
43 8125295 8010983 NM_021962 ABR link to infopage 0.627987 7.484001e-13 2.593506e-8 6.031409e-10
44 8125295 7962951 NM_003482 MLL2 link to infopage 0.625872 9.402814e-13 3.258451e-8 7.405571e-10
45 8178727 7905631 NM_023015 INTS3 link to infopage 0.625741 9.536777e-13 3.304875e-8 7.344166e-10
46 8125295 7977511 NM_007110 TEP1 link to infopage 0.624902 1.043469e-12 3.616038e-8 7.860951e-10
47 8125295 8168215 NM_005120 MED12 link to infopage 0.624851 1.049163e-12 3.635768e-8 7.735678e-10
48 8178727 7956301 NM_002332 LRP1 link to infopage 0.624686 1.067815e-12 3.700405e-8 7.709178e-10
49 8125295 7912166 NM_012102 RERE link to infopage 0.624154 1.130348e-12 3.917107e-8 7.994096e-10
50 8125295 7941694 NM_006328 RBM14 link to infopage 0.623741 1.181325e-12 4.093765e-8 8.187530e-10

Note that correlations with a raw p-value above 0.05 may have been removed from the results.

Correlation Browser: Daniel Sachse, Sjur Reppe, Kåre Gautvik - 2013.

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