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Correlations in the blood dataset

A typical search starts with inserting an identifier in the first window of “Search Options”, either Entrez Gene ID (e.g., “1234”), an Accession Number (e.g., “BE644809” or “NM_005715”), a Gene Symbol (e.g., “NR3C1” or “CREB1”, not case-sensitive) or an Affymetrix probe set ID (e.g., “8114814”).

Then, a specific transcript can be traced by inserting a second identifier in window two under “Search Options”. Alternatively, the window may be left open to obtain a list of the transcripts most significantly correlating to the identifier in the first window.

Filling in boxes in the “output options” fields enables restriction of output to e.g., transcripts having specific keywords in Gene Ontology (GO), TFs (genes having “transcription” as part of the Gene Title) or only positive or negative correlations.

(View the full list of available key terms [here]).

Search Options: Find correlations between...
Gene/Label/Number: and (Empty also means "all others")
Output Options
Restrict output to miRs, Transcription factors? (Empty: No restrictions.)
  with keyword:
 KEGG Pathway:
Limit output to rows.
Remove "self correlations", i.e. correlations of a variable with itself
Sort results by positive, negative or absolute value of correlation
Starting timer.
Connected to database on
User requested variable id 17061.
Evaluating targets, filters and restrictions...

Finding correlations with 1 variable:
id Label1 AccNum GeneSym Info Gene Name
17061 8149116 NM_005217 DEFA3 link to infopage defensin, alpha 3, neutrophil-specific

Fetching correlation data, please wait...
Getting list of correlations for id 17061.
Getting list of p-values for id 17061.
1 of 1 done.
Calculating corrections for multiple testing (n=17327), please wait...
Done; whole program took 0.071 seconds. Transmitting 50 results:

Column legend:

Rank Label1 Label2 AccNum GeneSym Info Pearson r Raw p Bonferroni FDR (BH)
1 8149116 8149126 NM_005217 DEFA3 link to infopage 1.000000 0.000000e+0 0.000000e+0 0.000000e+0
2 8149116 8149137 NM_005217 DEFA3 link to infopage 1.000000 0.000000e+0 0.000000e+0 0.000000e+0
3 8149116 8086607 NM_002343 LTF link to infopage 0.790569 1.139439e-23 1.974306e-19 6.581019e-20
4 8149116 8037222 NM_001816 CEACAM8 link to infopage 0.777965 1.631676e-22 2.827205e-18 7.068012e-19
5 8149116 8149109 NM_001925 DEFA4 link to infopage 0.770441 7.364812e-22 1.276101e-17 2.552202e-18
6 8149116 8062444 NM_001725 BPI link to infopage 0.746828 5.885842e-20 1.019840e-15 1.699733e-16
7 8149116 7951246 NM_002424 MMP8 link to infopage 0.699001 1.113875e-16 1.930011e-12 2.757159e-13
8 8149116 8158167 NM_005564 LCN2 link to infopage 0.616892 2.431507e-12 4.213072e-8 5.266340e-9
9 8149116 7969288 NM_006418 OLFM4 link to infopage 0.580552 8.499922e-11 1.472781e-6 1.636424e-7
10 8149116 8079590 NM_004345 CAMP link to infopage 0.549927 1.230829e-9 2.132658e-5 2.132658e-6
11 8149116 8126905 NM_006061 CRISP3 link to infopage 0.523979 9.682911e-9 1.677758e-4 1.525235e-5
12 8149116 8177222 NM_013230 CD24 link to infopage 0.404711 1.851369e-5 3.207867e-1 2.673223e-2
13 8149116 8031483 NM_001136134 RPL28 link to infopage -0.375482 7.916190e-5 1.371638e+0 1.055106e-1
14 8149116 7916568 AF263547 DAB1 link to infopage 0.356383 1.904027e-4 3.299108e+0 2.356506e-1
15 8149116 8024056 NM_001972 ELANE link to infopage 0.355768 1.956842e-4 3.390621e+0 2.260414e-1
16 8149116 8032284 NM_006830 UQCR11 link to infopage 0.351496 2.362755e-4 4.093945e+0 2.558716e-1
17 8149116 7914917 NM_032881 LSM10 link to infopage 0.350165 2.504284e-4 4.339173e+0 2.552455e-1
18 8149116 8155898 NM_006200 PCSK5 link to infopage -0.349046 2.629335e-4 4.555848e+0 2.531027e-1
19 8149116 8027268 BC067843 ZNF66 link to infopage -0.349001 2.634545e-4 4.564877e+0 2.402567e-1
20 8149116 7897801 NR_002754 RNU5E link to infopage 0.346775 2.901074e-4 5.026692e+0 2.513346e-1
21 8149116 hsa-miR-30e MI0000749 link to infopage 0.346684 2.912453e-4 5.046406e+0 2.403051e-1
22 8149116 7989277 NM_004998 MYO1E link to infopage -0.346124 2.983638e-4 5.169749e+0 2.349886e-1
23 8149116 7958000 NM_020244 CHPT1 link to infopage 0.336876 4.415416e-4 7.650592e+0 3.326344e-1
24 8149116 8142104 NM_152749 ATXN7L1 link to infopage -0.333160 5.151172e-4 8.925435e+0 3.718931e-1
25 8149116 8068671 NM_012105 BACE2 link to infopage 0.332953 5.195291e-4 9.001881e+0 3.600752e-1
26 8149116 8016213 ENST00000363083 link to infopage 0.332906 5.205292e-4 9.019209e+0 3.468926e-1
27 8149116 8121782 ENST00000410632 link to infopage 0.332709 5.247688e-4 9.092668e+0 3.367655e-1
28 8149116 7907690 NM_022371 TOR3A link to infopage 0.331047 5.617941e-4 9.734207e+0 3.476502e-1
29 8149116 8121596 BC146842 FAM26F link to infopage 0.328463 6.241879e-4 1.081530e+1 3.729415e-1
30 8149116 7910241 NM_000858 GUK1 link to infopage 0.325171 7.128319e-4 1.235124e+1 4.117079e-1
31 8149116 hsa-miR-181a-2-3p link to infopage -0.324516 7.318033e-4 1.267996e+1 4.090308e-1
32 8149116 8151991 ENST00000410165 link to infopage 0.324367 7.361744e-4 1.275569e+1 3.986154e-1
33 8149116 8149122 AF355799 DEFT1P link to infopage 0.323892 7.502779e-4 1.300007e+1 3.939414e-1
34 8149116 8149132 AF355799 DEFT1P link to infopage 0.323892 7.502779e-4 1.300007e+1 3.823549e-1
35 8149116 8103023 BC035666 link to infopage 0.323302 7.681456e-4 1.330966e+1 3.802760e-1
36 8149116 7938625 ENST00000391063 link to infopage 0.323120 7.737482e-4 1.340674e+1 3.724093e-1
37 8149116 8178508 NM_130463 ATP6V1G2 link to infopage -0.323098 7.744220e-4 1.341841e+1 3.626597e-1
38 8149116 7949377 NM_001997 FAU link to infopage 0.322020 8.083438e-4 1.400617e+1 3.685835e-1
39 8149116 8096025 ENST00000410322 link to infopage 0.320703 8.516006e-4 1.475568e+1 3.783509e-1
40 8149116 8149153 NR_027000 LOC349196 link to infopage -0.320136 8.708818e-4 1.508977e+1 3.772442e-1
41 8149116 8149157 NR_027000 LOC349196 link to infopage -0.320136 8.708818e-4 1.508977e+1 3.680432e-1
42 8149116 hsa-miR-376c MI0000776 link to infopage 0.319527 8.920359e-4 1.545631e+1 3.680073e-1
43 8149116 7967030 NR_003925 RNU4-1 link to infopage 0.319326 8.991292e-4 1.557921e+1 3.623072e-1
44 8149116 8078173 NM_138381 OXNAD1 link to infopage -0.317967 9.483570e-4 1.643218e+1 3.734587e-1
45 8149116 hsa-miR-296-5p link to infopage -0.317913 9.503879e-4 1.646737e+1 3.659416e-1
46 8149116 7949674 NM_031492 RBM4B link to infopage 0.316544 1.002565e-3 1.737145e+1 3.776402e-1
47 8149116 7983290 NM_001018108 SERF2 link to infopage 0.315716 1.035374e-3 1.793993e+1 3.817007e-1
48 8149116 8016628 NM_032595 PPP1R9B link to infopage 0.314423 1.088588e-3 1.886196e+1 3.929575e-1
49 8149116 8000899 NM_024671 ZNF768 link to infopage 0.312864 1.156047e-3 2.003083e+1 4.087925e-1
50 8149116 8151747 NM_001008495 TMEM64 link to infopage 0.312672 1.164625e-3 2.017946e+1 4.035893e-1

Note that correlations with a raw p-value above 0.05 may have been removed from the results.

Correlation Browser: Daniel Sachse, Sjur Reppe, Kåre Gautvik - 2013.

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