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Correlations in the blood dataset

A typical search starts with inserting an identifier in the first window of “Search Options”, either Entrez Gene ID (e.g., “1234”), an Accession Number (e.g., “BE644809” or “NM_005715”), a Gene Symbol (e.g., “NR3C1” or “CREB1”, not case-sensitive) or an Affymetrix probe set ID (e.g., “8114814”).

Then, a specific transcript can be traced by inserting a second identifier in window two under “Search Options”. Alternatively, the window may be left open to obtain a list of the transcripts most significantly correlating to the identifier in the first window.

Filling in boxes in the “output options” fields enables restriction of output to e.g., transcripts having specific keywords in Gene Ontology (GO), TFs (genes having “transcription” as part of the Gene Title) or only positive or negative correlations.

(View the full list of available key terms [here]).

Search Options: Find correlations between...
Gene/Label/Number: and (Empty also means "all others")
Output Options
Restrict output to miRs, Transcription factors? (Empty: No restrictions.)
  with keyword:
 KEGG Pathway:
Limit output to rows.
Remove "self correlations", i.e. correlations of a variable with itself
Sort results by positive, negative or absolute value of correlation
Starting timer.
Connected to database on
Searching for user input in variable labels, Entrez IDs, Accession Numbers...
Evaluating targets, filters and restrictions...

Finding correlations with 1 variable:
id Label1 AccNum GeneSym Info Gene Name
2272 7951246 NM_002424 MMP8 link to infopage matrix metallopeptidase 8 (neutrophil collagenase)

Fetching correlation data, please wait...
Getting list of correlations for id 2272.
Getting list of p-values for id 2272.
1 of 1 done.
Calculating corrections for multiple testing (n=17327), please wait...
Done; whole program took 0.107 seconds. Transmitting 50 results:

Column legend:

Rank Label1 Label2 AccNum GeneSym Info Pearson r Raw p Bonferroni FDR (BH)
1 7951246 8037222 NM_001816 CEACAM8 link to infopage 0.811473 8.983262e-26 1.556530e-21 1.556530e-21
2 7951246 8086607 NM_002343 LTF link to infopage 0.810009 1.285728e-25 2.227780e-21 1.113890e-21
3 7951246 8158167 NM_005564 LCN2 link to infopage 0.770722 6.969562e-22 1.207616e-17 4.025387e-18
4 7951246 8126905 NM_006061 CRISP3 link to infopage 0.769233 9.332896e-22 1.617111e-17 4.042777e-18
5 7951246 7969288 NM_006418 OLFM4 link to infopage 0.760076 5.362002e-21 9.290742e-17 1.858148e-17
6 7951246 8149109 NM_001925 DEFA4 link to infopage 0.742161 1.321782e-19 2.290251e-15 3.817086e-16
7 7951246 8062444 NM_001725 BPI link to infopage 0.708320 2.885442e-17 4.999606e-13 7.142294e-14
8 7951246 8149137 NM_005217 DEFA3 link to infopage 0.699001 1.113875e-16 1.930011e-12 2.412514e-13
9 7951246 8149126 NM_005217 DEFA3 link to infopage 0.699001 1.113875e-16 1.930011e-12 2.144457e-13
10 7951246 8149116 NM_005217 DEFA3 link to infopage 0.699001 1.113875e-16 1.930011e-12 1.930011e-13
11 7951246 8079590 NM_004345 CAMP link to infopage 0.665574 9.510482e-15 1.647881e-10 1.498074e-11
12 7951246 8149132 AF355799 DEFT1P link to infopage 0.415851 1.025527e-5 1.776930e-1 1.480775e-2
13 7951246 8149122 AF355799 DEFT1P link to infopage 0.415851 1.025527e-5 1.776930e-1 1.366869e-2
14 7951246 8024056 NM_001972 ELANE link to infopage 0.403277 1.994563e-5 3.455979e-1 2.468557e-2
15 7951246 8010030 NM_003857 GALR2 link to infopage 0.379439 6.554557e-5 1.135708e+0 7.571387e-2
16 7951246 8150014 NM_018250 INTS9 link to infopage -0.373661 8.627777e-5 1.494935e+0 9.343343e-2
17 7951246 8015846 NR_003562 MPP3 link to infopage 0.373198 8.818037e-5 1.527901e+0 8.987654e-2
18 7951246 8127743 NM_004242 HMGN3 link to infopage -0.370692 9.916851e-5 1.718293e+0 9.546071e-2
19 7951246 8144643 NM_002052 GATA4 link to infopage 0.367706 1.139182e-4 1.973860e+0 1.038874e-1
20 7951246 8143441 BC012493 KIAA1147 link to infopage -0.367642 1.142563e-4 1.979719e+0 9.898593e-2
21 7951246 8006409 NM_003885 CDK5R1 link to infopage 0.365876 1.239368e-4 2.147453e+0 1.022597e-1
22 7951246 8170695 NM_001395 DUSP9 link to infopage 0.364036 1.348330e-4 2.336252e+0 1.061933e-1
23 7951246 8154656 NM_022160 DMRTA1 link to infopage 0.363714 1.368303e-4 2.370858e+0 1.030808e-1
24 7951246 8014700 NM_001130677 C17orf96 link to infopage 0.362101 1.472509e-4 2.551417e+0 1.063090e-1
25 7951246 8005157 NM_004278 PIGL link to infopage -0.360142 1.608899e-4 2.787740e+0 1.115096e-1
26 7951246 7956200 NM_002475 MYL6B link to infopage 0.359099 1.686264e-4 2.921789e+0 1.123765e-1
27 7951246 8150962 NM_014729 TOX link to infopage -0.358691 1.717400e-4 2.975739e+0 1.102125e-1
28 7951246 7897426 NM_001215 CA6 link to infopage 0.358126 1.761420e-4 3.052013e+0 1.090005e-1
29 7951246 8101429 NM_016619 PLAC8 link to infopage -0.357886 1.780478e-4 3.085035e+0 1.063805e-1
30 7951246 7922596 AK096082 LOC646976 link to infopage 0.355431 1.986339e-4 3.441729e+0 1.147243e-1
31 7951246 8161618 NM_001163 APBA1 link to infopage 0.355254 2.001974e-4 3.468821e+0 1.118975e-1
32 7951246 8152079 NM_002568 PABPC1 link to infopage -0.352563 2.254666e-4 3.906660e+0 1.220831e-1
33 7951246 8167360 NM_002049 GATA1 link to infopage 0.352477 2.263222e-4 3.921484e+0 1.188329e-1
34 7951246 8034605 NM_052850 GADD45GIP1 link to infopage 0.351796 2.331879e-4 4.040446e+0 1.188367e-1
35 7951246 8068671 NM_012105 BACE2 link to infopage 0.350329 2.486432e-4 4.308242e+0 1.230926e-1
36 7951246 8052676 link to infopage 0.349064 2.627354e-4 4.552416e+0 1.264560e-1
37 7951246 8044640 NM_021965 PGM5 link to infopage 0.348445 2.698862e-4 4.676319e+0 1.263870e-1
38 7951246 8002072 BC008284 C16orf48 link to infopage 0.348006 2.750744e-4 4.766214e+0 1.254267e-1
39 7951246 8024038 NM_001700 AZU1 link to infopage 0.347757 2.780547e-4 4.817853e+0 1.235347e-1
40 7951246 8133504 NM_032999 GTF2I link to infopage -0.346695 2.911097e-4 5.044058e+0 1.261014e-1
41 7951246 8085665 NM_015150 RFTN1 link to infopage -0.346000 2.999605e-4 5.197415e+0 1.267662e-1
42 7951246 7942697 NM_004055 CAPN5 link to infopage 0.345593 3.052508e-4 5.289081e+0 1.259305e-1
43 7951246 8031483 NM_001136134 RPL28 link to infopage -0.345560 3.056769e-4 5.296463e+0 1.231736e-1
44 7951246 8001547 NM_015993 PLLP link to infopage 0.345446 3.071894e-4 5.322670e+0 1.209698e-1
45 7951246 7952601 NM_001143820 ETS1 link to infopage -0.344352 3.219369e-4 5.578200e+0 1.239600e-1
46 7951246 7938625 ENST00000391063 link to infopage 0.343092 3.397320e-4 5.886537e+0 1.279682e-1
47 7951246 8029870 NM_002517 NPAS1 link to infopage 0.341189 3.683277e-4 6.382014e+0 1.357875e-1
48 7951246 7943236 NM_002033 FUT4 link to infopage 0.340920 3.725418e-4 6.455032e+0 1.344798e-1
49 7951246 7923762 NM_018203 KLHDC8A link to infopage 0.340774 3.748443e-4 6.494928e+0 1.325495e-1
50 7951246 8000910 NM_145271 ZNF688 link to infopage 0.339612 3.936931e-4 6.821521e+0 1.364304e-1

Note that correlations with a raw p-value above 0.05 may have been removed from the results.

Correlation Browser: Daniel Sachse, Sjur Reppe, Kåre Gautvik - 2013.

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