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Correlations in the blood dataset

A typical search starts with inserting an identifier in the first window of “Search Options”, either Entrez Gene ID (e.g., “1234”), an Accession Number (e.g., “BE644809” or “NM_005715”), a Gene Symbol (e.g., “NR3C1” or “CREB1”, not case-sensitive) or an Affymetrix probe set ID (e.g., “8114814”).

Then, a specific transcript can be traced by inserting a second identifier in window two under “Search Options”. Alternatively, the window may be left open to obtain a list of the transcripts most significantly correlating to the identifier in the first window.

Filling in boxes in the “output options” fields enables restriction of output to e.g., transcripts having specific keywords in Gene Ontology (GO), TFs (genes having “transcription” as part of the Gene Title) or only positive or negative correlations.

(View the full list of available key terms [here]).

Search Options: Find correlations between...
Gene/Label/Number: and (Empty also means "all others")
Output Options
Restrict output to miRs, Transcription factors? (Empty: No restrictions.)
  with keyword:
 KEGG Pathway:
Limit output to rows.
Remove "self correlations", i.e. correlations of a variable with itself
Sort results by positive, negative or absolute value of correlation
Starting timer.
Connected to database on
Searching for user input in variable labels, Entrez IDs, Accession Numbers...
Evaluating targets, filters and restrictions...

Finding correlations with 2 variables:
id Label1 AccNum GeneSym Info Gene Name
16500 8180078 NM_002118 HLA-DMB link to infopage major histocompatibility complex, class II, DM beta
16562 8125530 NM_002118 HLA-DMB link to infopage major histocompatibility complex, class II, DM beta

Fetching correlation data, please wait...
Getting list of correlations for id 16500.
Getting list of p-values for id 16500.
1 of 2 done.
Getting list of correlations for id 16562.
Getting list of p-values for id 16562.
2 of 2 done.
Calculating corrections for multiple testing (n=34654), please wait...
Done; whole program took 0.237 seconds. Transmitting 50 results:

Column legend:

Rank Label1 Label2 AccNum GeneSym Info Pearson r Raw p Bonferroni FDR (BH)
1 8180078 8125530 NM_002118 HLA-DMB link to infopage 0.993864 2.564316e-100 8.886382e-96 8.886382e-96
2 8125530 8180078 NM_002118 HLA-DMB link to infopage 0.993864 2.564316e-100 8.886382e-96 4.443191e-96
3 8125530 8178193 NM_019111 HLA-DRA link to infopage 0.756247 1.088472e-20 3.771991e-16 1.257330e-16
4 8180078 8178193 NM_019111 HLA-DRA link to infopage 0.755315 1.290825e-20 4.473223e-16 1.118306e-16
5 8125530 8179481 NM_019111 HLA-DRA link to infopage 0.733584 5.592135e-19 1.937898e-14 3.875797e-15
6 8180078 8178884 NM_006120 HLA-DMA link to infopage 0.733259 5.899206e-19 2.044311e-14 3.407185e-15
7 8180078 8180086 NM_006120 HLA-DMA link to infopage 0.733259 5.899206e-19 2.044311e-14 2.920444e-15
8 8180078 8179481 NM_019111 HLA-DRA link to infopage 0.732826 6.334945e-19 2.195312e-14 2.744140e-15
9 8125530 8178884 NM_006120 HLA-DMA link to infopage 0.731385 8.022124e-19 2.779987e-14 3.088874e-15
10 8125530 8180086 NM_006120 HLA-DMA link to infopage 0.731385 8.022124e-19 2.779987e-14 2.779987e-15
11 8125530 8118548 NM_019111 HLA-DRA link to infopage 0.729877 1.025313e-18 3.553121e-14 3.230110e-15
12 8180078 8118548 NM_019111 HLA-DRA link to infopage 0.729380 1.111324e-18 3.851181e-14 3.209317e-15
13 8180078 8125537 NM_006120 HLA-DMA link to infopage 0.724507 2.425062e-18 8.403810e-14 6.464469e-15
14 8125530 8125537 NM_006120 HLA-DMA link to infopage 0.721076 4.159103e-18 1.441295e-13 1.029497e-14
15 8180078 8103508 NM_017923 MARCH1 link to infopage 0.719104 5.649711e-18 1.957851e-13 1.305234e-14
16 8125530 8103508 NM_017923 MARCH1 link to infopage 0.707934 3.054848e-17 1.058627e-12 6.616418e-14
17 8125530 7997712 NM_002163 IRF8 link to infopage 0.679059 1.696809e-15 5.880122e-11 3.458895e-12
18 8180078 7997712 NM_002163 IRF8 link to infopage 0.674004 3.272551e-15 1.134070e-10 6.300388e-12
19 8125530 8178199 link to infopage 0.672318 4.061971e-15 1.407635e-10 7.408607e-12
20 8125530 8179489 link to infopage 0.672318 4.061971e-15 1.407635e-10 7.038177e-12
21 8125530 8113039 NM_002397 MEF2C link to infopage 0.671390 4.572536e-15 1.584567e-10 7.545556e-12
22 8125530 8180100 NM_033554 HLA-DPA1 link to infopage 0.668932 6.243395e-15 2.163586e-10 9.834483e-12
23 8180078 7948364 NM_001039396 MPEG1 link to infopage 0.661062 1.660047e-14 5.752726e-10 2.501185e-11
24 8180078 8180100 NM_033554 HLA-DPA1 link to infopage 0.660902 1.692819e-14 5.866296e-10 2.444290e-11
25 8125530 7948364 NM_001039396 MPEG1 link to infopage 0.656758 2.799325e-14 9.700782e-10 3.880313e-11
26 8180078 8178199 link to infopage 0.654748 3.562247e-14 1.234461e-9 4.747928e-11
27 8180078 8179489 link to infopage 0.654748 3.562247e-14 1.234461e-9 4.572079e-11
28 8180078 8113039 NM_002397 MEF2C link to infopage 0.652904 4.437350e-14 1.537719e-9 5.491855e-11
29 8125530 8166730 NM_000397 CYBB link to infopage 0.648221 7.698544e-14 2.667853e-9 9.199495e-11
30 8180078 8011826 AY358809 C17orf87 link to infopage 0.648054 7.849667e-14 2.720224e-9 9.067412e-11
31 8125530 8011826 AY358809 C17orf87 link to infopage 0.643059 1.397553e-13 4.843078e-9 1.562283e-10
32 8125530 8054092 NM_015348 TMEM131 link to infopage 0.642105 1.558513e-13 5.400871e-9 1.687772e-10
33 8180078 8072015 NM_005160 ADRBK2 link to infopage 0.640861 1.795366e-13 6.221663e-9 1.885352e-10
34 8180078 8166730 NM_000397 CYBB link to infopage 0.639413 2.115269e-13 7.330254e-9 2.155957e-10
35 8125530 8094911 NM_020453 ATP10D link to infopage 0.638366 2.380059e-13 8.247855e-9 2.356530e-10
36 8125530 8102848 NM_030648 SETD7 link to infopage 0.637307 2.680525e-13 9.289092e-9 2.580303e-10
37 8180078 8102848 NM_030648 SETD7 link to infopage 0.633280 4.195140e-13 1.453784e-8 3.929146e-10
38 8125530 8072015 NM_005160 ADRBK2 link to infopage 0.632110 4.772326e-13 1.653802e-8 4.352110e-10
39 8180078 7919971 NM_000449 RFX5 link to infopage 0.631469 5.120267e-13 1.774377e-8 4.549685e-10
40 8180078 8115147 NM_001025159 CD74 link to infopage 0.627955 7.509764e-13 2.602434e-8 6.506084e-10
41 8125530 7955908 NM_005337 NCKAP1L link to infopage 0.627847 7.598571e-13 2.633209e-8 6.422460e-10
42 8180078 8054092 NM_015348 TMEM131 link to infopage 0.627021 8.308404e-13 2.879194e-8 6.855224e-10
43 8125530 8079392 NM_001123396 CCR2 link to infopage 0.626741 8.563427e-13 2.967570e-8 6.901325e-10
44 8180078 7955908 NM_005337 NCKAP1L link to infopage 0.625659 9.620907e-13 3.334029e-8 7.577339e-10
45 8180078 8094911 NM_020453 ATP10D link to infopage 0.624387 1.102566e-12 3.820834e-8 8.490741e-10
46 8180078 8079392 NM_001123396 CCR2 link to infopage 0.623644 1.193644e-12 4.136455e-8 8.992293e-10
47 8125530 7919971 NM_000449 RFX5 link to infopage 0.622960 1.283789e-12 4.448843e-8 9.465624e-10
48 8125530 8178891 NM_033554 HLA-DPA1 link to infopage 0.622035 1.416457e-12 4.908592e-8 1.022623e-9
49 8125530 8125556 NM_033554 HLA-DPA1 link to infopage 0.622035 1.416457e-12 4.908592e-8 1.001753e-9
50 8125530 8112428 NM_005582 CD180 link to infopage 0.620371 1.688873e-12 5.852621e-8 1.170524e-9

Note that correlations with a raw p-value above 0.05 may have been removed from the results.

Correlation Browser: Daniel Sachse, Sjur Reppe, Kåre Gautvik - 2013.

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